Pepitem May Reduce Risk of Obesity and Type 2 Diabetes? People are talking about peptides that reduce the risks involved with Type 2 Diabetes, due to the new popularity of semaglutide. This article is about a new and different peptide that is showing great promise.
If you are overweight and have been struggling, like so many of us are, you’re probably concerned about the possibility of developing type 2 diabetes. Many long-term health problems, such as diabetes and other metabolic disorders, are linked to being overweight. This can make you more likely to get sick. Making healthy choices is vital to lower your risk of getting ill.
Besides making changes to your lifestyle, many studies have shown that there may be additional ways to lower your risk of getting type 2 diabetes. One way to do this is to add a peptide that occurs naturally to your regular routine. This has been shown to reduce risk greatly, and it could be a useful weapon in the fight against this long-term disease.
What are Peptides?
Peptides are molecules composed of a sequence of two or more amino acids and are often called the building blocks of proteins. They can help reduce wrinkles and other indications of aging to soothe pain and help strengthen muscles. Peptides can operate as hormones or neurotransmitters and can also work with proteins to control how the body works.
Additionally, some peptides have been shown to improve mental clarity and enhance cognitive performance. As such, peptides are becoming increasingly popular among those looking for natural ways to stay healthy and youthful.
Obesity and Diabetes
Extra weight and body fat can cause big changes in how fat works in our bodies. This can hurt the pancreas and make the body less sensitive to insulin. Too much body fat, along with high blood sugar, is very detrimental to our health.
Also, too much fat on our bodies causes a low systemic inflammatory response all over the body. This inflammatory response causes white blood cells to flood into various tissues. This causes even more health problems that will harm a person’s health in the long run.
Link Between Peptide and Obesity
Clinical and Experimental Immunology published a study on the adiponectin-PEPTIDE pathway’s potential to prevent diabetes. The study showed how this pathway could be used to stop alterations in the pancreas before diabetes develops.
This could be potentially beneficial for those at risk of developing diabetes, as it suggests that there may be an opportunity to stop its onset 1https://www.medicalnewstoday.com/articles/a-natural-peptide-could-help-tackle-obesity-and-diabetes.
Using mice in the study, researchers experimented to see if giving a peptide called PEPITEM through a pump might stop or reverse the effects of a high-fat diet on the pancreas.
The mice that were given PEPITEM showed a considerable reduction of insulin-producing cells in the pancreas. They also showed a drop in the number of white blood cells that were found in fat tissue deep in the belly and in the organs in the abdominal cavity.
These results from PEPITEM were encouraging, showing lower system-wide inflammation, and also a healthier pancreas.
After testing PEPITEM on mice, the researchers concluded that it shows “promising effects” for human physiology. Researchers were optimistic that their findings would hold true in people despite having only tested them on rats. Therefore, more studies of PEPITEM’s effects on humans are required2https://academic.oup.com/cei/advance-article/doi/10.1093/cei/uxad022/7073686.
There need to be more studies done on PEPITEM before we can draw any firm conclusions about its potential to reduce obesity and diabetes. Nonetheless, these results provide a reason for hope for future treatments for these diseases. Furthermore, PEPITEM looks to offer a workable answer in the fight against the worldwide epidemics of obesity and diabetes.
Dr. Helen McGettrick is the one who led the study. She shared her insights about their findings:
“Using an animal model of obesity, we showed that a small peptide called PEPITEM can limit the number of immune cells entering into a variety of tissues across the body, and it also reduces the size of insulin-producing cells in the pancreas.”
“Immune cell movement into tissues is an important protective response to infection and tissue damage. However, uncontrolled immune cell migration underpins tissue damage in a number of chronic diseases, including obesity, type 2 diabetes, and cardiovascular disease. In type 2 diabetes, the insulin-producing cells of the pancreas increase in size and number as they become damaged.”
“These preclinical data suggest that PEPITEM may offer a new therapy that could halt the onset of type 2 diabetes in obese individuals,” Dr. McGettrick added3https://www.medicalnewstoday.com/articles/a-natural-peptide-could-help-tackle-obesity-and-diabetes.
Now we all want to know how to get ahold of this peptide! However, we will have to wait until further studies are completed successfully.
Her tragic family history of Type 2 Diabetes, and her own diagnosis of prediabetes in 2021 caused her to research more deeply, leading to a passion in educating people on how to hopefully put this disease into remission.
